Berkeley CSUA MOTD:Entry 25258
Berkeley CSUA MOTD
2019/04/22 [General] UID:1000 Activity:popular

2002/7/2 [Science/Biology] UID:25258 Activity:kinda low
7/1     This is your brain. This is your brain on pot. Pot is harmless. Use it.
        \_ well the Japs are skitzo to begin with, so the data may be skewed.
                    \________\_ the educated response...
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United Press International Gene glitches link pot with schizophrenia Published 7/1/2002 5:06 PM OKAYAMA, Japan, July 1 (UPI) -- Genetic anomalies tied with marijuana-activated brain chemicals appear linked to schizophrenia, Japanese researchers report. Schizophrenia is one of the greatest mental health challenges in the world, affecting roughly one of every 100 people and filling about a quarter of all hospital beds in the United States. For years, clinical scientists have known that abusing marijuana, also known as cannabis, can trigger hallucinations and delusions similar to symptoms often found in schizophrenia. Prior studies also show that cannabis used before age 18 raises the risk of schizophrenia six-fold. The hallucinogenic properties of marijuana, the researchers explained, are linked to a biochemical found abundantly in the brain. The chemical, called cannabinoid receptor protein, studs the surfaces of brain cells and latches onto the active chemical within marijuana known as THC. Ujike and his team examined the gene for the marijuana receptor in 121 Japanese patients with schizophrenia and an average age of 44. When they compared this gene in schizophrenics with the same gene in 148 normal men and woman of the same average age, they found distinct abnormalities in DNA sequences called nucleotides among the schizophrenics. Some of their nucleotides in the marijuana receptor gene appeared significantly more often than normal while others appeared less frequency. This holds especially true for a condition called hebephrenic schizophrenia, which is marked by deterioration of personality, senseless laughter, disorganized thought and lack of motivation. These symptoms are similar to psychotic behavior sometimes triggered by severe cannabis abuse, which could mean the marijuana receptors in schizophrenics are far more active than they should be. Ujike stressed there is no evidence yet these genetic abnormalities can affect how the marijuana receptor actually acts in the brain. The researchers described their findings in the scientific journal Molecular Psychiatry. Copyright 2004 United Press International Copyright 2001-2004 United Press International.